BIOHIT Celiac quick test

Reliable first-line diagnostics

BIOHIT Celiac quick test is a qualitative in vitro immunochromatographic test aiding in diagnosis of celiac disease by detecting antibodies (IgA/IgG/IgM) against human tissue transglutaminase in whole blood, plasma or serum samples. This rapid test can be used by healthcare professionals, either in a laboratory-based or Point-of-Care (POC) setting. The results are available from a fingertip blood sample already within ten minutes. Each BIOHIT Celiac quick test kit contains reagents for 20 tests.

Key benefits

Determination of tTG IgA/G/M antibodies (reduces risk of IgA deficient false negatives)
For use in the physicians office, Outpatient Dietetic Clinics, Pharmacies
Simple and safe procedure
High accuracy
Results in 10 minutes

Celiac Disease (CD) is an enteropathy characterized by a permanent intolerance to gluten, specifically to its protein fragment, gliadin. Iingestion of this protein by the person with genetic predisposition induces a severe mucosal injury of the small intestine, histologically characterized by hyperplasia of the crypts, and subtotal or total atrophy of the intestinal microvilli. The definitive diagnosis of celiac disease is based on characteristic histological changes in intestinal biopsies, but serological tests such as the detection of anti-gliadin, anti-tTG and anti-endomysium antibodies, offer cost-effective and less invasive methods of diagnosing CD. It is estimated that over 1% of the global population is affected by CD.

In patients with coeliac disease autoantibodies are produced against endomysium – a component of smooth muscle connective tissue. The major antigen of anti-endomysium antibodies is tissue transglutaminase (tTG). Human tTG can be used in diagnostic tests to capture and detect the anti-tTG antibodies and form the basis of a very accurate screening test. It is particularly useful for pediatric patients to reduce the need of endoscopies.