Human Extracellular Matrix Components (ECM)

The extracellular matrix (ECM) consists of interstitial connective tissue and basement membrane (BM). The ECM acts as a backbone for cells and provides a physical barrier. It also influences such functions as cell proliferation, differentiation, adhesion, migration, gene expression, and tissue integrity.

ECM also plays a profound role in tissue injury and healing. The detection of ECM components in various parts of the body provides an efficient tool for following malignant change, invasion and metastasis. Biohit provides monoclonal antibodies to fi – bronectins(1,2,3), tenascin(4,5), laminin(6,7) and vitronectin.