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Human Integrins

Yleistä

Integrins are the largest known family of receptors for ECM proteins. They are glycoproteins that  mediate cell-extracellular matrix as well as cell-cell interactions. Integrins consist of several protein subfamilies that share a common

Ohjeet

Datasheets:

Monoclonal antibody to b1 INTEGRIN clone DF5 (IgG1)

100 µg immunoglobulin in 1 ml PBS solution containing 1.0% (w/v) BSA and 0.1% (w/v) sodium azide.

The product is for research use only. The performance characteristics of this product have not been established. Use in human clinical diagnosis is the responsibility of the user. This product should be stored
at +2 … +8 °C.

Monoclonal antibody (Mab) to b1 integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Wheat germ agglutinin binding glycoproteins of human fibroblasts were used as immunogen.

Specificity
The antibody reacts with the b1 subunit of the integrin protein family and seems to be human specific. The antibody reacts with an extracellular epitope of the b1 integrin molecule.

Applications
Immunohistochemical stainings, western blotting and other immunoassays for cellular and tumor biology. Mab DF5 does react with paraffin sections (2).

Guidelines for dilutions
Working dilution in western blotting is at least 1:1000.

Monoclonal antibody to b1 INTEGRIN clone DF7 (IgG1)

100 µg immunoglobulin in 1 ml PBS solution containing 1.0% (w/v) BSA and 0.1% (w/v) sodium azide.

The product is for research use only. The performance characteristics of this product have not been established. Use in human clinical diagnosis is the responsibility of the user. This product should be stored
at +2 … +8 °C.

Monoclonal antibody to b1 integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Wheat germ agglutinin binding glycoproteins of human fibroblasts were used as immunogen.

Specificity
The antibody reacts with the b1 subunit of the integrin protein family. The monoclonal antibody reacts with an extracellular epitope of the b1 integrin molecule.

Applications
Immunohistochemical stainings, western blotting and other immunoassays for cellular and tumor biology. Works with paraffin-embedded sections.

Guidelines for dilutions
Working dilution in western blotting is at least 1:1000.


Monoclonal antibody to  b3 INTEGRIN - clone BB10 (IgG1)

100 µg immunoglobulin in 1 ml PBS solution containing 1.0% (w/v) BSA and 0.1% (w/v) sodium azide.

The product is for research use only. The performance characteristics of this product have not been established. Use in human clinical diagnosis is the responsibility of the user. This product should be stored
at +2 … +8 °C.

Monoclonal antibody to b3 integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Partially purified platelet glycoprotein IIb/IIIa complex was used as an immunogen.

Specificity
The antibody reacts with b3 integrin including the GPIIIa of platelets.

Applications
Immunohistochemical stainings, western blotting and other immunoassays for cellular and tumor biology.

Guidelines for dilutions
Working dilution in western blotting is at least 1:1000.


Monoclonal antibody to aIIb INTEGRINclone CA3 (IgG1)

100 µg immunoglobulin in 1 ml PBS solution containing 1.0% (w/v) BSA and 0.1% (w/v) sodium azide.

The product is for research use only. The performance characteristics of this product have not been established. Use in human clinical diagnosis is the responsibility of the user. This product should be stored
at +2 … +8 °C.

Monoclonal antibody to aIIb integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Partially purified platelet glycoprotein IIb/IIIa complex was used as an immunogen.

Specificity
The antibody reacts with the aIIb-subunit of the b-integrins. Reacts specifically with platelets, megakaryocytes and leukemic cells able to megakaryocytic differentiation.

Applications
Immunohistochemical stainings, western blotting and other immunoassays for cellular and tumor biology.

Guidelines for dilutions
Working dilution in western blotting is at least 1:1000.


Tilaus

Tuote Spesifisyys Klooni Host Alaluokka Formaatti Määrä Sovellukset Parafiini Tilausnro Kysely
Human Integrins ß1 -Integrin DF5 mouse IgG1 purified 100 μg IHC, WB yes 610008 Kysely
Human Integrins ß1 -Integrin DF5 mouse IgG1 purified 1mg IHC, WB yes 610035 Kysely
Human Integrins ß1 -Integrin DF7 mouse IgG1 purified 100 μg IHC, WB yes 610009 Kysely
Human Integrins ß1 -Integrin DF7 mouse IgG1 purified 1mg IHC, WB yes 610036 Kysely
Human Integrins ß3 -Integrin BB10 mouse IgG1 purified 100 μg IHC, WB no 610010 Kysely
Human Integrins ß3 -Integrin BB10 mouse IgG1 purified 1mg IHC, WB no 610037 Kysely
Human Integrins αIIb-Integrin CA3 mouse IgG1 purified 100 μg IHC, WB no 610011 Kysely
Human Integrins αIIb-Integrin CA3 mouse IgG1 purified 1mg IHC, WB no 610038 Kysely

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